منابع مشابه
Too much or too little
The global effort to understand the molecular drivers of cancer onset and progression is now coming to fruition with the identification of specific genomic and epigenomic events that influence signaling through key oncogenic pathways. Genetic studies using inducible expression of the critical growth controlling oncogenes MYC, RAS, PI3K and AKT have shown unequivocally that, in conjunction with ...
متن کاملSaying too Little and Saying too Much
You are going to Paul’s party tonight. You have a long day of work ahead of you before that, but you can’t wait to get there. Your annoying friend comes up to you and says, ‘Hi! Oh, are you going to Paul’s party tonight? I don’t think I’ll go. Unless your going?’ You reply, ‘I have to work.’ There are lies and then there are misleading utterances that are not lies. You did not lie to your frien...
متن کاملToo much PABP, too little translation.
Posttranscriptional regulation is of critical importance during mammalian spermiogenesis. A set of mRNAs that encode proteins critical to normal sperm formation are synthesized early in the process of male germ cell differentiation and are stored in a repressed state. These mRNAs are subsequently translationally activated during the process of spermatid elongation and maturation. Of note, the t...
متن کاملPediatric psychopharmacology: Too much and too little.
This paper provides a selective overview of the past, present and future of pediatric psychopharmacology. The acceptance of medication use in child psychiatry was based on the results of double-blind, placebo-controlled trials documenting the efficacy of drug treatments for attention-deficit/hyperactivity disorder, enuresis, depression, anxiety disorders, obsessive-compulsive disorder and psych...
متن کاملToo Much Glucagon, Too Little Insulin
OBJECTIVE To determine the time course of changes in glucagon and insulin secretion in children with recently diagnosed type 1 diabetes. RESEARCH DESIGN AND METHODS Glucagon and C-peptide concentrations were determined in response to standard mixed meals in 23 patients with type 1 diabetes aged 9.4 +/- 4.6 years, beginning within 6 weeks of diagnosis, and every 3 months thereafter for 1 year....
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ژورنال
عنوان ژورنال: Journal of Public Economics
سال: 2012
ISSN: 0047-2727
DOI: 10.1016/j.jpubeco.2011.08.005